Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 1.00 |
| ▸ | BCL2L1 | Q07817 | 12/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131218 | 0.97 | BCL2 (0.95) | BCL2BCL2L1HDAC1HDAC6 | |
| SCHEMBL29131191 | 0.95 | BCL2 (1.00) | BCL2BCL2L1HDAC1HDAC6 | |
| SCHEMBL29131199 | 0.94 | BCL2 (0.95) | BCL2BCL2L1HDAC1HDAC6 | |
| SCHEMBL29131196 | 0.93 | BCL2 (0.86) | BCL2BCL2L1 | |
| SCHEMBL29131194 | 0.91 | BCL2 (0.90) | BCL2BCL2L1 | |
| SCHEMBL29463355 | 0.90 | BCL2 (0.82) | BCL2BCL2L1HDAC1HDAC6 | |
| SCHEMBL30682039 | 0.90 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL21412871 | 0.90 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL21412867 | 0.90 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL29131188 | 0.90 | BCL2 (1.00) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369094-B | Trifluoromethyl substituted sulfonamide selective BCL-2 inhibitors | 正大天晴药业集团股份有限公司 | 2023-09-29 | — | — | CN | disclosed |