Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553770 | 1.00 | NPSR1 (0.41) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL1330697 | 0.77 | NPSR1 (0.43) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL17050984 | 0.77 | NPSR1 (0.43) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL11662478 | 0.74 | ANPEP (0.43) | TSHR | |
| SCHEMBL366215 | 0.73 | NPY5R (0.50) | NPSR1KCNH2POLBACHEMAPT | |
| Hydrogen Peroxide SCHEMBL8609887 | 0.72 | NPY5R (0.49) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL914767 | 0.72 | NPY5R (0.49) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL916329 | 0.72 | NPY5R (0.49) | NPSR1KCNH2POLBACHEMAPT | |
| SCHEMBL9000152 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL777260 | 0.70 | TP53 (0.46) | MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117303992-A | Preparation method of polyfunctional group substituted chiral sulfoxide compound | 厦门大学 | 2023-12-29 | — | — | CN | claimed |