Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.71 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | TLR3 | O15455 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148483 | 0.83 | KIT (0.62) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL564035 | 0.83 | KIT (1.00) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL31060598 | 0.83 | KIT (1.00) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL17212473 | 0.83 | KIT (0.76) | KITPDGFRAFGFR3RECQLKDM4E | |
| Hydrochloric Acid SCHEMBL8821075 | 0.82 | KIT (0.97) | KITPDGFRAFGFR3RECQLKDM4E | |
| Bromide SCHEMBL10413309 | 0.82 | KIT (0.97) | KITPDGFRAFGFR3RECQLKDM4E | |
| Hydrochloric Acid SCHEMBL15517783 | 0.82 | KIT (0.97) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL29289480 | 0.82 | KIT (0.60) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL3342543 | 0.81 | KIT (0.72) | KITPDGFRAFGFR3RECQLKDM4E | |
| SCHEMBL31362096 | 0.81 | KIT (1.00) | KITPDGFRAFGFR3RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279952-A | Methods for treating cancer using subcutaneous administration of anti-PD 1 antibodies | 默沙东有限责任公司 | 2023-12-22 | — | — | CN | disclosed |