SCHEMBL29132503

SCHEMBL29132503

CC(C)(C)OC(=O)CNc1c(OCc2ccccc2)cc2c(c1F)C[C@H](NC(=O)OC(C)(C)C)CC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
ACHE P22303 2/20 0.43
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
RORC P51449 2/20 0.37
TAOK1 Q7L7X3 1/20 0.37
TAOK3 Q9H2K8 1/20 0.37
SCN9A Q15858 1/20 0.36
DRD2 P14416 2/20 0.36
PAX8 Q06710 1/20 0.36
KCNA3 P22001 1/20 0.35
KDM1A O60341 1/20 0.35
MAOB P27338 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
PDE4B Q07343 1/20 0.35
EPHX2 P34913 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626234 1.00 CA1 (0.43) CA1CA2ACHEKMT2AL3MBTL1
SCHEMBL29626370 0.95 CA1 (0.50) CA1CA2ACHERORCTAOK1
SCHEMBL22412225 0.95 CA1 (0.50) CA1CA2ACHERORCTAOK1
SCHEMBL22412223 0.95 CA1 (0.50) CA1CA2ACHERORCTAOK1
SCHEMBL25338361 0.94 CA1 (0.44) CA1CA2ACHEKMT2AL3MBTL1
SCHEMBL29626442 0.87 ACACB (0.39) KMT2ADRD2MEN1
SCHEMBL29132482 0.85 CA1 (0.46) CA1CA2ACHEKMT2AL3MBTL1
SCHEMBL28691654 0.83 CA1 (0.32) CA1CA2ACHEL3MBTL1DRD2
SCHEMBL30352483 0.82 KMT2A (0.39) CA1CA2ACHEKMT2AL3MBTL1
SCHEMBL29626343 0.81 KMT2A (0.39) CA1CA2ACHEKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829555-A Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2023-09-29 CN disclosed