Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400097 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL17451842 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL208304 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL17453181 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL13242445 | 1.00 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL2742456 | 0.86 | CA1 (0.39) | CA1CA2CA12CA9PPM1B | |
| SCHEMBL12357210 | 0.85 | PPM1B (0.39) | LMNAPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL2127524 | 0.85 | PPM1B (0.39) | LMNAPPM1BPTPN1PPP1CCALDH1A1 | |
| SCHEMBL1128162 | 0.84 | CA1 (0.38) | CA1CA2CA12CA9LMNA | |
| SCHEMBL30158792 | 0.84 | CA1 (0.38) | CA1CA2CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |