Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201974 | 0.87 | PRKCE (0.34) | SOS1PRKCEMAPTKDM4ETSHR | |
| SCHEMBL29132959 | 0.86 | SOS1 (0.41) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL29133019 | 0.86 | LCK (0.41) | PRKCEMAPTKDM4ETSHRLMNA | |
| SCHEMBL24516625 | 0.81 | SOS1 (0.43) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL29128003 | 0.81 | SOS1 (0.40) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL25619919 | 0.81 | SOS1 (0.46) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL25676979 | 0.81 | SOS1 (0.41) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL1044961 | 0.80 | SOS1 (0.46) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL20557111 | 0.79 | SOS1 (0.44) | SOS1CA12CA1CA2CA7 | |
| SCHEMBL22400318 | 0.79 | SOS1 (0.44) | SOS1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |