SCHEMBL29133437

SCHEMBL29133437

O=c1ccc2ccc(OCCCCBr)cc2o1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 10/20 0.73
CA9 Q16790 10/20 0.73
CA1 P00915 9/20 0.73
CA6 P23280 5/20 0.73
CA7 P43166 5/20 0.73
CA14 Q9ULX7 5/20 0.73
CA4 P22748 5/20 0.73
CA5B Q9Y2D0 3/20 0.73
CA2 P00918 3/20 0.73
CA3 P07451 3/20 0.73
CA5A P35218 3/20 0.68
MAOB P27338 9/20 0.68
MAOA P21397 8/20 0.68
CYP1A2 P05177 1/20 0.63
KCNA3 P22001 1/20 0.60
KCNA5 P22460 1/20 0.60
NPC1 O15118 2/20 0.57
MEN1 O00255 1/20 0.57
MTNR1A P48039 1/20 0.57
KMT2A Q03164 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704386 1.00 CA12 (0.73) CA12CA9CA1CA6CA7
SCHEMBL28067301 0.98 CA12 (0.71) CA12CA9CA1CA6CA7
SCHEMBL10697689 0.98 CA12 (0.71) CA12CA9CA1CA6CA7
SCHEMBL12679312 0.98 CA12 (0.71) CA12CA9CA1CA6CA7
SCHEMBL7883068 0.95 CA12 (0.75) CA12CA9CA1CA6CA7
SCHEMBL6590585 0.91 CA12 (0.72) CA12CA9CA1CA6CA7
SCHEMBL24045405 0.91 CA12 (0.82) CA12CA9CA1CA6CA7
SCHEMBL31086804 0.88 CA12 (0.77) CA12CA9CA1CA6CA7
SCHEMBL31086623 0.88 CA12 (0.77) CA12CA9CA1CA6CA7
SCHEMBL12304245 0.87 CA12 (0.81) CA12CA9CA1CA6CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327065-A Carbazole derivatives as dopamine D2/3 receptor modulators 北京大学 2024-01-02 CN disclosed