SCHEMBL29133520

SCHEMBL29133520

c1ccc2c(-c3cc(-c4ccncc4)cc(-c4cccc5ccccc45)n3)cccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 2/20 0.53
MAPK1 P28482 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPK11 Q15759 2/20 0.49
MAPK14 Q16539 2/20 0.49
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TNF P01375 1/20 0.45
BCHE P06276 1/20 0.44
MAPK13 O15264 1/20 0.44
GCGR P47871 1/20 0.44
MAPK12 P53778 1/20 0.44
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17945864 0.98 KDM4E (0.51) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343415 0.98 KDM4E (0.51) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17945866 0.95 KDM4E (0.49) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343417 0.95 KDM4E (0.49) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17932289 0.92 MAPK11 (0.50) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343348 0.89 KDM4E (0.52) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343416 0.89 HTR2C (0.46) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343418 0.89 CYP19A1 (0.55) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17944718 0.87 KDM4E (0.57) KDM4EALDH1A1MAPTHPGDMAPK1
SCHEMBL17343350 0.86 KDM4E (0.50) KDM4EALDH1A1MAPTHPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114891134-B Multicolor adjustable dynamic fluorescent ionic polymer, preparation method and application 常州大学 2023-11-24 CN claimed
CN-114891134-A Multicolor adjustable dynamic fluorescent ionic polymer, preparation method and application 常州大学 2022-08-12 CN claimed
CN-114891134-B Multicolor adjustable dynamic fluorescent ionic polymer, preparation method and application 常州大学 2023-11-24 CN disclosed
CN-114891134-B Multicolor adjustable dynamic fluorescent ionic polymer, preparation method and application 常州大学 2023-11-24 CN disclosed
CN-114891134-A Multicolor adjustable dynamic fluorescent ionic polymer, preparation method and application 常州大学 2022-08-12 CN disclosed