Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133714 | 0.81 | SLC29A1 (0.60) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29775125 | 0.80 | EGFR (0.60) | DYRK1ALMNAEGFRPIK3CA | |
| SCHEMBL24576523 | 0.80 | EGFR (0.60) | DYRK1ALMNAEGFRPIK3CA | |
| SCHEMBL29133712 | 0.79 | MAPK1 (0.55) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29133726 | 0.78 | MAPK1 (0.61) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29133700 | 0.77 | DYRK1A (0.56) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29133730 | 0.77 | CLK4 (0.52) | DYRK1AMAPK1LMNAEGFRHTT | |
| Formamide SCHEMBL29133744 | 0.76 | MAPK1 (0.51) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29133727 | 0.76 | PIK3CA (0.65) | DYRK1AMAPK1LMNAEGFRHTT | |
| SCHEMBL29133751 | 0.76 | EGFR (0.68) | DYRK1AMAPK1LMNAEGFRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295716-A | Substituted aminobenzyl heteroaryl compounds as EGFR and/or PI3K inhibitors | 麦克尼斯迪克治疗有限公司 | 2023-12-26 | — | — | CN | disclosed |