Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904710 | 0.91 | CDK2 (0.36) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2912417 | 0.89 | CCNE1 (0.33) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2904144 | 0.85 | CCNE1 (0.36) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2945701 | 0.82 | CDK2 (0.49) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL2910404 | 0.81 | BCDIN3D (0.35) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2911086 | 0.81 | CCNE1 (0.36) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2907796 | 0.81 | CLK1 (0.43) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2913808 | 0.80 | CDK2 (0.35) | CCNE1CDK2CCNE2CDK5CDK5R1 | |
| SCHEMBL2913278 | 0.80 | SYK (0.34) | BCDIN3DCCNE1CDK2CCNE2CCNA2 | |
| SCHEMBL2910096 | 0.80 | CLK1 (0.40) | BCDIN3DCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348707-B1 | Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy | USTAV EX BOTAN AV CR V V I I O (CZ) | 2010-08-25 | — | — | EP | disclosed |
| US-7745450-B2 | Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy | INSTITUTE OF EXPERIMENTAL BOTANY (CZ) | 2010-06-29 | — | — | US | disclosed |
| EP-1348707-A1 | Pyrazolo[4,3-d]pyrimidines, processes for their preparation and methods for therapy | Ustav Experimentalni Botaniky AV CR (Institute of Experimental Botany Academy of Sciences of the Czech Republic) (CZ) | 2003-10-01 | — | — | EP | disclosed |