SCHEMBL29134339

SCHEMBL29134339

CC1(C)Cc2cc(Br)ccc2C1NS(C)(=O)=O

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 0.32
KDM1A O60341 2/20 0.32
SLC22A12 Q96S37 1/20 0.31
STS P08842 2/20 0.31
BRD4 O60885 1/20 0.31
APP P05067 1/20 0.31
METAP1 P53582 1/20 0.30
ALDH1A1 P00352 2/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30014797 1.00 SRD5A1 (0.32) SRD5A1KDM1ASLC22A12STSBRD4
SCHEMBL23361904 0.78 CAMK2A (0.36) SRD5A1ALDH1A1POLBTSHR
SCHEMBL27029774 0.78 CAMK2A (0.36) SRD5A1ALDH1A1POLBTSHR
SCHEMBL30701804 0.72
SCHEMBL31490352 0.72
SCHEMBL27128333 0.72
SCHEMBL30701789 0.72
SCHEMBL27029783 0.72
SCHEMBL1530500 0.72 GRIA2 (0.44) SRD5A1
SCHEMBL31490434 0.71 KDM1A (0.44) KDM1ASLC6A2HTR2AHTR2CSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120429-A KHK inhibitor 吉利德科学公司 2023-11-24 CN disclosed