Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134829 | 1.00 | NR1H2 (0.48) | NR1H2NAMPTMEN1KMT2AHPGD | |
| SCHEMBL24033163 | 1.00 | NR1H2 (0.48) | NR1H2NAMPTMEN1KMT2AHPGD | |
| SCHEMBL24816012 | 0.92 | NR1H2 (0.43) | NR1H2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24033631 | 0.92 | NR1H2 (0.43) | NR1H2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24033635 | 0.92 | NR1H2 (0.43) | NR1H2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24032960 | 0.90 | NR1H2 (0.51) | NR1H2NAMPTMEN1KMT2AHPGD | |
| SCHEMBL21193622 | 0.83 | HPGD (0.47) | NR1H2HPGDUSP2SMN1; SMN2RECQL | |
| SCHEMBL25949587 | 0.82 | NR1H2 (0.40) | NR1H2NAMPTMEN1KMT2AHPGD | |
| SCHEMBL2459787 | 0.81 | NR1H2 (0.51) | NR1H2NAMPTMEN1KMT2AHPGD | |
| SCHEMBL22565169 | 0.80 | NR1H2 (0.45) | NR1H2NAMPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997548-A | HTT modulators for the treatment of huntington's disease | CHDI基金会股份有限公司 | 2023-11-03 | — | — | CN | disclosed |