Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770799 | 1.00 | NR1H2 (0.42) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL16914071 | 0.84 | NR1H2 (0.40) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL29770741 | 0.82 | NR1H2 (0.43) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL26783375 | 0.82 | NR1H2 (0.43) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL7407281 | 0.82 | NR1H2 (0.43) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL29770833 | 0.81 | NR1H2 (0.42) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL26906883 | 0.81 | NR1H2 (0.42) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL22047153 | 0.79 | NR1H2 (0.41) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL21996489 | 0.79 | NR1H2 (0.41) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL30545919 | 0.78 | NR1H2 (0.40) | NR1H2MEN1KMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022165529-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | JANSSEN BIOTECH, INC. (US) | 2022-08-04 | — | — | WO | disclosed |