Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29041471 | 0.95 | KDM4E (0.51) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL28405103 | 0.93 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL28377616 | 0.93 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL3916643 | 0.86 | KDM4E (0.51) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL15012422 | 0.81 | KDM4E (0.50) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL15012403 | 0.80 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL15012254 | 0.80 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL15012872 | 0.80 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL15012395 | 0.80 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A | |
| SCHEMBL3914664 | 0.80 | KDM4E (0.52) | LONP1KDM4EMAPTTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997548-A | HTT modulators for the treatment of huntington's disease | CHDI基金会股份有限公司 | 2023-11-03 | — | — | CN | disclosed |