Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135102 | 0.87 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28483827 | 0.82 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28489703 | 0.82 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28485168 | 0.81 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL29135101 | 0.81 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28479514 | 0.79 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL29135090 | 0.78 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28483830 | 0.78 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28480588 | 0.78 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11EGFR | |
| SCHEMBL28479501 | 0.77 | MAPK13 (0.42) | MAPK14MAPK13MAPK12MAPK11EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936496-B | Heterocyclic compounds useful as medicaments | 马萨里克大学 | 2023-12-29 | — | — | CN | disclosed |