SCHEMBL29135220

SCHEMBL29135220

FC(F)(F)c1ccc2cscc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.46
PTPN5 P54829 1/20 0.42
METAP2 P50579 1/20 0.41
EPHX2 P34913 1/20 0.39
SCN4A P35499 1/20 0.39
MPL P40238 2/20 0.39
CYBB P04839 1/20 0.38
NOX3 Q9HBY0 1/20 0.38
NOX4 Q9NPH5 1/20 0.38
NOX1 Q9Y5S8 1/20 0.38
KDM4E B2RXH2 1/20 0.37
PIM1 P11309 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
KIF11 P52732 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
PTPN1 P18031 3/20 0.35
CES2 O00748 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588186 0.80 BACE1 (0.56) BACE1PTPN5METAP2EPHX2SCN4A
SCHEMBL12895896 0.75 BACE1 (0.52) BACE1PTPN5METAP2EPHX2SCN4A
SCHEMBL12895889 0.75 BACE1 (0.52) BACE1PTPN5METAP2EPHX2SCN4A
SCHEMBL12320899 0.71 BACE1 (0.48) BACE1PTPN5METAP2KDM4EPIM1
SCHEMBL12473661 0.71 BACE1 (0.48) BACE1PTPN5METAP2KDM4EPIM1
SCHEMBL1538767 0.71 PTPN1 (0.59) BACE1METAP2CYBBNOX3NOX4
SCHEMBL12310186 0.71 BACE1 (0.48) BACE1PTPN5METAP2KDM4EPIM1
SCHEMBL30985267 0.71 PTPN1 (0.59) BACE1METAP2CYBBNOX3NOX4
SCHEMBL30706974 0.71 PTPN1 (0.59) BACE1METAP2CYBBNOX3NOX4
SCHEMBL9804973 0.70 PTPN1 (0.52) BACE1METAP2CYBBNOX3NOX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304233-A Iridium metal complex, application thereof and organic electroluminescent device 清华大学 2023-12-29 CN disclosed