Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298190 | 0.80 | HTR2A (0.42) | MMEHTR2ATAAR1CYP2A6IDO1 | |
| SCHEMBL25278064 | 0.77 | TAAR1 (0.46) | MMEHTR2ATAAR1IDO1 | |
| SCHEMBL8030764 | 0.76 | ACACB (0.45) | MMETAAR1ACACB | |
| SCHEMBL28771437 | 0.76 | MME (0.40) | MMEHTR2ATAAR1CYP2A6IDO1 | |
| SCHEMBL3041534 | 0.76 | TAAR1 (0.44) | MMEHTR2ATAAR1CYP2A6IDO1 | |
| SCHEMBL28771432 | 0.76 | MME (0.40) | MMEHTR2ATAAR1CYP2A6IDO1 | |
| SCHEMBL1427338 | 0.76 | ACACB (0.45) | MMETAAR1ACACB | |
| SCHEMBL8584002 | 0.76 | IGF1R (0.45) | MMEHTR2ATAAR1SLC18A3 | |
| SCHEMBL28771438 | 0.76 | MME (0.40) | MMEHTR2ATAAR1CYP2A6IDO1 | |
| SCHEMBL3151427 | 0.75 | EPHX1 (0.50) | MMETAAR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |