Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.62 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872749 | 0.88 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL30032171 | 0.88 | TLR7 (0.62) | TLR7TLR8 | |
| SCHEMBL6722230 | 0.86 | TLR7 (0.77) | TLR7TLR8 | |
| SCHEMBL26981086 | 0.85 | TLR7 (0.72) | TLR7TLR8 | |
| SCHEMBL26981091 | 0.84 | TLR7 (0.74) | TLR7TLR8 | |
| SCHEMBL26981129 | 0.83 | TLR7 (0.65) | TLR7TLR8 | |
| SCHEMBL26981069 | 0.82 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL24732770 | 0.80 | TLR7 (0.66) | TLR7TLR8 | |
| SCHEMBL29136653 | 0.79 | TLR7 (0.67) | TLR7TLR8 | |
| SCHEMBL28872784 | 0.79 | TLR7 (0.50) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |