Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.75 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947634 | 1.00 | TLR7 (0.75) | TLR7TLR8PDE4APDE4BPDE4C | |
| SCHEMBL29136647 | 0.91 | TLR7 (0.64) | TLR7TLR8 | |
| SCHEMBL26981108 | 0.89 | TLR7 (0.60) | TLR7TLR8PDE4APDE4BPDE4C | |
| SCHEMBL29947815 | 0.85 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29136641 | 0.85 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL29136618 | 0.85 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL30824675 | 0.85 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL26981101 | 0.84 | TLR7 (0.66) | TLR7TLR8PDE4APDE4BPDE4C | |
| SCHEMBL29947672 | 0.84 | TLR7 (0.66) | TLR7TLR8PDE4APDE4BPDE4C | |
| SCHEMBL4754020 | 0.81 | TLR7 (0.49) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |