Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.39 |
| ▸ | TYK2 | P29597 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29879507 | 1.00 | KLKB1 (0.39) | KLKB1TYK2ABL1LRRK2METTL3 | |
| SCHEMBL29136913 | 1.00 | KLKB1 (0.39) | KLKB1TYK2ABL1LRRK2METTL3 | |
| SCHEMBL29302879 | 1.00 | KLKB1 (0.39) | KLKB1TYK2ABL1LRRK2METTL3 | |
| SCHEMBL29136865 | 1.00 | KLKB1 (0.39) | KLKB1TYK2ABL1LRRK2METTL3 | |
| SCHEMBL29304087 | 0.90 | TYK2 (0.36) | TYK2ABL1LRRK2JAK2 | |
| SCHEMBL29939911 | 0.90 | TYK2 (0.36) | TYK2ABL1LRRK2JAK2 | |
| SCHEMBL24739028 | 0.90 | KLKB1 (0.41) | KLKB1TYK2LRRK2METTL3 | |
| SCHEMBL29879342 | 0.90 | KLKB1 (0.40) | KLKB1ABL1LRRK2METTL3 | |
| SCHEMBL24737549 | 0.90 | KLKB1 (0.40) | KLKB1ABL1LRRK2METTL3 | |
| SCHEMBL29879270 | 0.90 | KLKB1 (0.41) | KLKB1TYK2LRRK2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |