Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.76 |
| ▸ | PDE4A | P27815 | 11/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15270505 | 0.87 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7357641 | 0.86 | PDE4D (0.83) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7137903 | 0.83 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7353637 | 0.81 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL30614194 | 0.80 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL2908650 | 0.80 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL6874729 | 0.80 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL30084831 | 0.80 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7371319 | 0.80 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL985307 | 0.79 | PDE4B (0.82) | PDE4DPDE4APDE4BPDE4CCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |