Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29879417 | 1.00 | KLKB1 (0.31) | KLKB1 | |
| SCHEMBL24738288 | 0.90 | — | — | |
| SCHEMBL30997786 | 0.90 | — | — | |
| SCHEMBL24739093 | 0.90 | — | — | |
| SCHEMBL24737563 | 0.89 | CYP17A1 (0.34) | KLKB1 | |
| SCHEMBL30997781 | 0.89 | CYP17A1 (0.34) | KLKB1 | |
| SCHEMBL24737810 | 0.88 | — | — | |
| SCHEMBL29305550 | 0.87 | MKNK1 (0.34) | — | |
| SCHEMBL24737697 | 0.86 | BTK (0.33) | KLKB1 | |
| SCHEMBL29879140 | 0.86 | BTK (0.33) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |