SCHEMBL29137792

SCHEMBL29137792

O=S(=O)(CCCl)c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
APEX1 P27695 1/20 0.47
F2 P00734 3/20 0.45
PRSS1 P07477 3/20 0.45
PRSS2 P07478 3/20 0.45
PRSS3 P35030 3/20 0.45
HTR6 P50406 2/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SCN1A P35498 2/20 0.42
SCN2A Q99250 2/20 0.42
SCN3A Q9NY46 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25413517 0.88 APEX1 (0.58) CA1CA2CA9APEX1MEN1
SCHEMBL7393267 0.88 CA1 (0.49) CA1CA2CA9APEX1F2
SCHEMBL7394073 0.86 CA1 (0.47) CA1CA2CA9APEX1F2
SCHEMBL1813055 0.85 CA1 (0.57) CA1CA2CA9APEX1F2
SCHEMBL9097798 0.83 CA1 (0.55) CA1CA2CA9APEX1F2
SCHEMBL7886519 0.81 CA1 (0.53) CA1CA2CA9APEX1F2
SCHEMBL10908053 0.81 CA1 (0.53) CA1CA2CA9APEX1F2
SCHEMBL10908050 0.81 CA1 (0.53) CA1CA2CA9APEX1F2
SCHEMBL2703626 0.81 CA1 (0.53) CA1CA2CA9APEX1F2
SCHEMBL9097803 0.81 CA1 (0.53) CA1CA2CA9APEX1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117157277-A 1, 6-naphthalene dithiol and process for producing the same 菅井化学工业株式会社 2023-12-01 CN disclosed