Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728175 | 0.91 | ELANE (0.56) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL24294955 | 0.91 | ELANE (0.56) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL27338339 | 0.85 | NPC1 (0.49) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL27338982 | 0.85 | NPC1 (0.49) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL23759544 | 0.85 | MAPT (0.43) | ELANEDHODHHPRT1MAPTNPC1 | |
| SCHEMBL26031592 | 0.84 | DHODH (0.44) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL24466886 | 0.83 | ELANE (0.51) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL27338952 | 0.83 | DHODH (0.48) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL22880605 | 0.82 | ESR1 (0.46) | ELANEDHODHMAPTNPC1RAB9A | |
| SCHEMBL27338525 | 0.81 | DHODH (0.44) | ELANEDHODHMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874153-B | Synthetic method of naphtho [2,1-d ] oxazole compound | 湖南第一师范学院 | 2023-11-17 | — | — | CN | disclosed |