Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30609840 | 1.00 | PIK3CA (0.62) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL30609839 | 0.88 | PIK3CA (0.65) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL29139493 | 0.88 | PIK3CA (0.65) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL29139502 | 0.87 | PIK3CA (0.48) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL923836 | 0.83 | PIK3CB (0.67) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30609827 | 0.80 | PIK3CA (0.56) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL25777353 | 0.78 | PIK3CA (0.70) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL30609818 | 0.77 | PIK3CA (0.50) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29139472 | 0.76 | PIK3CG (0.39) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR | |
| SCHEMBL30609833 | 0.76 | PIK3CG (0.39) | PIK3CAPIK3CDPIK3CBPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891469-A | Thiazole derivative and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-10-17 | — | — | CN | disclosed |