Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912404 | 0.91 | CRBN (0.39) | CRBNCYP3A4BRD4 | |
| SCHEMBL2916365 | 0.91 | CRBN (0.40) | CRBNCYP3A4BRD4 | |
| SCHEMBL2908256 | 0.91 | CRBN (0.42) | CRBNCYP3A4 | |
| SCHEMBL2913169 | 0.90 | CRBN (0.40) | CRBNCYP3A4EPHX2 | |
| SCHEMBL2914788 | 0.89 | CRBN (0.39) | CRBNCYP3A4 | |
| SCHEMBL2915572 | 0.89 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL2913326 | 0.87 | CRBN (0.38) | CRBNCYP3A4 | |
| SCHEMBL2915746 | 0.85 | CRBN (0.37) | CRBNCYP3A4 | |
| SCHEMBL2910760 | 0.85 | CRBN (0.33) | CRBN | |
| SCHEMBL2912660 | 0.85 | CRBN (0.32) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |