Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.47 |
| ▸ | CDK8 | P49336 | 7/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19341716 | 0.84 | BCL2 (0.49) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL20578175 | 0.84 | BCL2 (0.49) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL29398024 | 0.84 | BCL2 (0.49) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL523456 | 0.84 | CDK8 (0.49) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL31427495 | 0.84 | CDK8 (0.49) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL19867779 | 0.83 | BCL2 (0.48) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL19867929 | 0.83 | CDK8 (0.52) | BCL2BCL2L1CDK8KDRTNIK | |
| SCHEMBL19839529 | 0.78 | BCL2 (0.51) | BCL2BCL2L1CDK8ALK | |
| SCHEMBL1702063 | 0.78 | BCL2 (0.50) | BCL2BCL2L1CDK8ABL1ALK | |
| SCHEMBL19867786 | 0.78 | BCL2 (0.50) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |