Ethylene Glycol

Ethylene Glycol

SCHEMBL29142091

O=C1CCC(C2=CCCCC2)CC1.OCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.40
MAPT P10636 1/20 0.39
KDM1A O60341 1/20 0.38
CCR2 P41597 1/20 0.32
GSTP1 P09211 1/20 0.31
CYP19A1 P11511 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
NPC1 O15118 1/20 0.30
EPHX1 P07099 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29142093 0.91 KDM1A (0.44) ESR2MAPTKDM1ACCR2CYP19A1
SCHEMBL2496561 0.85 MAPT (0.46) ESR2MAPTKDM1ACYP19A1TRIM24
SCHEMBL22477542 0.79 MAPT (0.57) ESR2MAPTKDM1ACCR2TRIM24
SCHEMBL9278172 0.77 KDM1A (0.50) MAPTKDM1ACCR2HDAC4HDAC2
SCHEMBL5668812 0.77
SCHEMBL122872 0.75 KDM1A (0.50) MAPTKDM1ACCR2HDAC4HDAC2
SCHEMBL14973454 0.75 KDM1A (0.50) MAPTKDM1AHDAC4HDAC2HDAC8
SCHEMBL14973453 0.75 KDM1A (0.50) MAPTKDM1AHDAC4HDAC2HDAC8
SCHEMBL11683805 0.75 KDM1A (0.45) MAPTKDM1AHDAC2
SCHEMBL1904517 0.75 KDM1A (0.50) MAPTKDM1ACCR2HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894181-A Synthetic method of cyclohexenyl cyclohexyl difluorobenzene liquid crystal compound 渭南高新区海泰新型电子材料有限责任公司 2023-04-04 CN disclosed