Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6247121 | 0.96 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| Ammonia Solution, Strong SCHEMBL27888916 | 0.96 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| Bromide SCHEMBL8559956 | 0.92 | CA1 (0.39) | CA1CA2CA4CA12CA7 | |
| SCHEMBL41646 | 0.92 | CA1 (0.43) | CA1CA2CA4CA12CA7 | |
| SCHEMBL7702552 | 0.92 | CA1 (0.43) | CA1CA2CA4CA12CA7 | |
| SCHEMBL23589703 | 0.88 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| SCHEMBL6470270 | 0.88 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| SCHEMBL31540317 | 0.88 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| SCHEMBL29576072 | 0.88 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| SCHEMBL23589702 | 0.88 | CA1 (0.41) | CA1CA2CA4CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115915782-A | Preparation method of interface modified perovskite film | 陕西科技大学 | 2023-04-04 | — | — | CN | disclosed |