SCHEMBL29145153

SCHEMBL29145153

CCCN(CCC)C(=O)n1cnc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
RAB9A P51151 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ASAH1 Q13510 6/20 0.53
LMNA P02545 2/20 0.48
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
BCHE P06276 1/20 0.47
APAF1 O14727 1/20 0.46
HTT P42858 1/20 0.45
P2RX1 P51575 2/20 0.44
P2RX4 Q99571 2/20 0.44
P2RX3 P56373 1/20 0.44
STAT6 P42226 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29145117 0.92 ASAH1 (0.57) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL30723161 0.90 ASAH1 (0.60) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL29145137 0.90 ASAH1 (0.60) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL29145140 0.89 SMN1; SMN2 (0.64) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL10533752 0.85 SMN1; SMN2 (0.56) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL29145086 0.82 SMN1; SMN2 (0.59) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL2184004 0.80 SMN1; SMN2 (0.72) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL16596879 0.77 SMN1; SMN2 (0.64) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL11012986 0.76 NPC1 (0.57) SMN1; SMN2NPC1ALDH1A1MAPTHPGD
SCHEMBL24110360 0.76 SMN1; SMN2 (0.58) SMN1; SMN2NPC1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN claimed
CN-117430738-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed
CN-117430737-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2024-01-23 CN disclosed