Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 4/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29145805 | 1.00 | KDR (0.53) | KDRRAF1TRPV1MAPTRAB9A | |
| SCHEMBL29145803 | 0.95 | KDR (0.54) | KDRRAF1TRPV1MAPTRAB9A | |
| SCHEMBL29145806 | 0.89 | TRPV1 (0.52) | KDRRAF1TRPV1BRAF | |
| SCHEMBL30681162 | 0.87 | KDR (0.61) | KDRRAF1TRPV1MAPTRAB9A | |
| SCHEMBL28418798 | 0.86 | BRAF (0.55) | KDRRAF1TRPV1MAPTBRAF | |
| SCHEMBL28416461 | 0.85 | KDR (0.61) | KDRRAF1TRPV1CA1CA2 | |
| SCHEMBL28416463 | 0.85 | KDR (0.61) | KDRRAF1TRPV1CA1CA2 | |
| SCHEMBL620123 | 0.85 | KDR (0.67) | KDRRAF1TRPV1MAPTMEN1 | |
| SCHEMBL30681201 | 0.82 | KDR (0.62) | KDRRAF1TRPV1MAPTRAB9A | |
| SCHEMBL30681177 | 0.81 | KDR (0.72) | KDRTRPV1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217722-B | Azo aryl urea derivative, and preparation method and application thereof | 华东理工大学 | 2024-01-02 | — | — | CN | disclosed |