SCHEMBL2914633

SCHEMBL2914633

O=C(OC1CCC2OC2C1)OC1CCC2OC2C1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 4/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
PMP22 Q01453 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
THPO P40225 1/20 0.38
PPM1B O75688 2/20 0.37
PTPN1 P18031 2/20 0.37
PPP1CC P36873 2/20 0.37
PPP1CA P62136 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21747530 0.87 TFPI2 (0.38) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL28479319 0.86 PPM1B (0.35) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL7930114 0.85 TFPI2 (0.41) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL28023248 0.84 PPM1B (0.32) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL28673876 0.83 ATM (0.40) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL28673874 0.83 ATM (0.40) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL4179061 0.83 CHRM2 (0.40) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL11755781 0.82 TSHR (0.37) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL28089674 0.82 TFPI2 (0.39) TFPI2LMNAKDM4EGMNNPMP22
SCHEMBL17923255 0.81 KCNA3 (0.34) PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084131-B2 Transparent hybrid sheet SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-12-27 US disclosed
US-20100216912-A1 TRANSPARENT HYBRID SHEET SUMITOMO BAKELITE CO., LTD. 2010-08-26 US disclosed
EP-2154169-A1 TRANSPARENT COMPOSITE SHEET Sumitomo Bakelite Co., Ltd. (JP) 2010-02-17 EP disclosed
US-4038338-A NEW POLYEPOXIDE-POLYSILOXANE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed