Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751571 | 0.89 | PDE10A (0.51) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| SCHEMBL3751570 | 0.89 | PDE10A (0.51) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| SCHEMBL3751561 | 0.87 | AOC3 (0.53) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| SCHEMBL3751556 | 0.87 | AOC3 (0.53) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| SCHEMBL3751565 | 0.87 | AOC3 (0.53) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2923493 | 0.86 | AOC3 (0.52) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2923490 | 0.86 | AOC3 (0.52) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL3763018 | 0.86 | AOC3 (0.52) | L3MBTL1TDP1MAPTLMNAKMT2A | |
| SCHEMBL2923395 | 0.83 | MAPT (0.52) | MAPTLMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8261943 | 0.78 | KMT2A (0.69) | L3MBTL1TDP1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | Pharmaxis Ltd. (AU) | 2010-09-01 | — | — | EP | claimed |
| WO-2009066152-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (US) | 2009-05-28 | — | — | WO | claimed |