Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943134 | 0.87 | PDGFRB (0.63) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL27486435 | 0.84 | MAPT (0.77) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL30080115 | 0.84 | PDGFRB (0.59) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL23726472 | 0.84 | PDGFRB (0.59) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2919716 | 0.83 | PDGFRB (1.00) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL29055040 | 0.83 | PDGFRB (0.58) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL23727245 | 0.82 | PDGFRB (0.57) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL23726881 | 0.82 | PDGFRB (0.57) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL30080064 | 0.82 | PDGFRB (0.57) | PDGFRBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL2912881 | 0.82 | PDGFRB (1.00) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882717-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2010-09-08 | — | — | EP | disclosed |