SCHEMBL291480

SCHEMBL291480

CCC([C]=O)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10995808 0.77
SCHEMBL873410 0.76
SCHEMBL20551243 0.76
SCHEMBL891222 0.76
SCHEMBL974860 0.74
SCHEMBL8018180 0.74
SCHEMBL31367824 0.73 GRIK1 (0.32)
SCHEMBL14639213 0.72 TSHR (0.30)
SCHEMBL15626947 0.70
SCHEMBL893423 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3758668-B1 PROCESS FOR PREPARING MICROCAPSULES FIRMENICH & CIE (CH) 2022-02-23 EP disclosed
US-20210129104-A1 PROCESS FOR PREPARING MICROCAPSULES FIRMENICH SA (CH) 2021-05-06 US disclosed
EP-3758668-A1 PROCESS FOR PREPARING MICROCAPSULES Firmenich SA (CH) 2021-01-06 EP disclosed
WO-2020020829-A1 PROCESS FOR PREPARING MICROCAPSULES FIRMENICH SA (CH) 2020-01-30 WO disclosed
EP-2970295-B1 PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2016-12-28 EP disclosed
US-9458164-B2 Pyrrolopyridazines as potassium ion channel inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2016-10-04 US disclosed
US-20160016961-A1 PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2016-01-21 US disclosed
EP-2970295-A1 PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS Bristol-Myers Squibb Company (US) 2016-01-20 EP disclosed
WO-2014143607-A1 PYRROLOPYRIDAZINES AS POTASSIUM ION CHANNEL INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-18 WO disclosed
EP-2321319-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2012-03-14 EP disclosed
US-8044068-B2 Aminopyrrolidine compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-10-25 US disclosed
US-7998950-B2 Antiviral compounds GILEAD SCIENCES, INC. (US) 2011-08-16 US disclosed
EP-2321319-A1 ANTIVIRAL COMPOUNDS Gilead Sciences, Inc. (US) 2011-05-18 EP disclosed
WO-2010011959-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-01-28 WO disclosed
US-20100022508-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-01-28 US disclosed
US-20090291940-A1 AMINOPYRROLIDINE COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2009-11-26 US disclosed
EP-2003131-A1 AMINOPYRROLIDINE COMPOUND Taisho Pharmaceutical Co. Ltd. (JP) 2008-12-17 EP disclosed
EP-0553130-B1 PYRROLIDINE DIONE DERIVATIVES PFIZER (US) 1996-01-03 EP disclosed
EP-0553130-A1 PYRROLIDINE DIONE DERIVATIVES. PFIZER (US) 1993-08-04 EP disclosed
WO-1992006954-A2 PYRROLIDINE DIONE DERIVATIVES PFIZER INC. (US) 1992-04-30 WO disclosed