SCHEMBL2915048

SCHEMBL2915048

CC(C)(C)C#CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6111770 0.72
SCHEMBL10619155 0.72
SCHEMBL4119428 0.71
SCHEMBL6251504 0.67
SCHEMBL6257844 0.67 KMT2A (0.33)
SCHEMBL6110328 0.66
SCHEMBL3596776 0.65
SCHEMBL179477 0.64
SCHEMBL6257842 0.64
SCHEMBL2161853 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119592076-A Surface flexible heat-conducting silicon rubber composite material and preparation method thereof 江苏大学 2025-03-11 CN claimed
CN-116669412-A Heterostructure heat-conducting electromagnetic shielding silicone rubber and preparation method thereof 常州宏巨电子科技有限公司 2023-08-29 CN claimed
EP-2016065-B1 1-(BENZO[D][1,3]DIOXOL-5-YL)-N-(PHENYL)CYCLOPROPANE-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS FOR THE TREATMENT OF CYSTIC FIBROSIS VERTEX PHARMA (US) 2012-09-19 EP claimed
EP-1509551-B1 PROCESS FOR PURIFICATION OF ALKOXYSTYRENE POLYMERS DUPONT ELECTRONIC POLYMERS L P (US) 2010-07-07 EP claimed
EP-1817287-B1 AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS LILLY CO ELI (US) 2010-02-10 EP claimed
CN-119592076-A Surface flexible heat-conducting silicon rubber composite material and preparation method thereof 江苏大学 2025-03-11 CN disclosed
CN-118900839-A Antiviral compounds and methods of making and using the same 吉利德科学公司 2024-11-05 CN disclosed
CN-114585628-B Modulators of cystic fibrosis transmembrane conductance regulator 弗特克斯药品有限公司 2024-03-26 CN disclosed
CN-117285547-A Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation 弗特克斯药品有限公司 2023-12-26 CN disclosed
CN-112004817-B Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation 弗特克斯药品有限公司 2023-06-23 CN disclosed
CN-115996928-A 1' -cyanonucleoside analogs and uses thereof 吉利德科学公司 2023-04-21 CN disclosed
US-20210046070-A1 LANTHIONINE SYNTHETASE C-LIKE 2-BASED THERAPEUTICS LANDOS BIOPHARMA, INC. (US) 2021-02-18 US disclosed
US-20200392131-A1 COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS Arvinas, Inc. 2020-12-17 US disclosed
US-20170067874-A1 Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-03-09 US disclosed
US-9315505-B2 Heterocyclic compounds and uses thereof INTELLIKINE LLC (US) 2016-04-19 US disclosed
US-20140296207-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INTELLIKINE, INC. 2014-10-02 US disclosed