SCHEMBL2915213

SCHEMBL2915213

CC(=O)CC(=O)OCC=NO

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.44
GAA P10253 2/20 0.44
SI P14410 2/20 0.44
MGAM2 Q2M2H8 2/20 0.44
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2915211 1.00 MGAM (0.44) MGAMGAASIMGAM2HTT
SCHEMBL27865778 1.00 MGAM (0.44) MGAMGAASIMGAM2HTT
SCHEMBL27882158 0.80 MGAM (0.46) MGAMGAASIMGAM2HTT
SCHEMBL27882156 0.80 MGAM (0.46) MGAMGAASIMGAM2HTT
SCHEMBL27713834 0.79 MGAM (0.40) MGAMGAASIMGAM2
SCHEMBL27641880 0.78
SCHEMBL8744844 0.78
SCHEMBL27997655 0.78
SCHEMBL16667687 0.76 MGAM (0.50) MGAMGAASIMGAM2HTT
SCHEMBL28125722 0.76 MGAM (0.50) MGAMGAASIMGAM2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111072515-B Method for continuously synthesizing thiaminoximic acid intermediate 普洛药业股份有限公司 2023-02-28 CN claimed
CN-111072515-A Method for continuously synthesizing thiaminoximic acid intermediate 山东普洛得邦医药有限公司 2020-04-28 CN claimed
CN-111072515-B Method for continuously synthesizing thiaminoximic acid intermediate 普洛药业股份有限公司 2023-02-28 CN disclosed
CN-111072515-B Method for continuously synthesizing thiaminoximic acid intermediate 普洛药业股份有限公司 2023-02-28 CN disclosed
CN-111072515-A Method for continuously synthesizing thiaminoximic acid intermediate 山东普洛得邦医药有限公司 2020-04-28 CN disclosed
CN-111072515-A Method for continuously synthesizing thiaminoximic acid intermediate 山东普洛得邦医药有限公司 2020-04-28 CN disclosed
CN-110218194-A A kind of the 3- methyl-quinoxaline -2- carboxylic acid and its synthetic method of stable isotope labeling 上海安谱实验科技股份有限公司 2019-09-10 CN disclosed
CN-109689631-A Method for preparing 3- (trifluoromethyl) pyrazine-2-formic ether 隆萨有限公司 2019-04-26 CN disclosed
CN-102603746-B Carbapenem derivative KBP BIOSCIENCES CO LTD 2015-07-15 CN disclosed
EP-2223969-B1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME MITSUI CHEMICALS INC (JP) 2015-02-25 EP disclosed
US-8648130-B2 Resin composition, transparent member obtained from the resin composition, and use of the same MITSUI CHEMICALS, INC. (JP) 2014-02-11 US disclosed
CN-102603746-A Carbapenem derivative KBP BIOSCIENCES CO LTD 2012-07-25 CN disclosed
US-20100256271-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME MITSUI CHEMICALS, INC. (JP) 2010-10-07 US disclosed
EP-2223969-A1 RESIN COMPOSITION, TRANSPARENT MEMBER OBTAINED FROM THE RESIN COMPOSITION, AND USE OF THE SAME Mitsui Chemicals, Inc. (JP) 2010-09-01 EP disclosed
CN-1960984-B Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as MGLU5 receptor antagonists HOFFMANN LA ROCHE 2010-05-12 CN disclosed
CN-1960984-A Pyridin-4-yl-ethynyl-imidazoles and pyrazoles as MGLU5 receptor antagonists HOFFMANN LA ROCHE (CH) 2007-05-09 CN disclosed