Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.54 |
| ▸ | HRH1 | P35367 | 19/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2915319 | 0.89 | HRH1 (0.65) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL13177118 | 0.88 | HRH1 (0.66) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL3282868 | 0.84 | CCR3 (0.56) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL6129274 | 0.76 | HRH1 (0.80) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL2922740 | 0.76 | HRH1 (0.80) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL5990826 | 0.74 | HRH1 (0.55) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL6650906 | 0.73 | HRH1 (0.53) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL2916656 | 0.73 | HRH1 (0.82) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL1931012 | 0.72 | HRH1 (0.63) | CCR3HRH1KCNH2CCR1 | |
| SCHEMBL6650218 | 0.72 | HRH1 (0.61) | CCR3HRH1KCNH2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478624-B1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2010-09-08 | — | — | EP | disclosed |
| US-7709500-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20050107428-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107428-A1 | Chemical compounds | CCR10, CCR3, CXCR5 | CCR3 2/4885HRH1 33/4885KCNH2 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.