Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.68 |
| ▸ | FLT4 | P35916 | 6/20 | 0.68 |
| ▸ | FLT1 | P17948 | 3/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.48 |
| ▸ | MET | P08581 | 4/20 | 0.45 |
| ▸ | AURKA | O14965 | 3/20 | 0.45 |
| ▸ | TEK | Q02763 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753477 | 1.00 | KDR (0.68) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL30753468 | 0.91 | KDR (0.68) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL29153414 | 0.91 | KDR (0.68) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL29153406 | 0.90 | KDR (0.64) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL29153409 | 0.90 | KDR (0.64) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL30753471 | 0.90 | KDR (0.64) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL11931698 | 0.90 | KDR (0.83) | KDRFLT4FLT1METAURKA | |
| SCHEMBL29153415 | 0.89 | KDR (0.59) | KDRFLT4FLT1PDGFRBMET | |
| SCHEMBL30753460 | 0.84 | KDR (0.67) | KDRFLT4FLT1 | |
| SCHEMBL30753459 | 0.84 | KDR (0.67) | KDRFLT4FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | claimed |
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | disclosed |