Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.58 |
| ▸ | FLT1 | P17948 | 4/20 | 0.58 |
| ▸ | FLT4 | P35916 | 4/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753474 | 1.00 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753476 | 0.94 | KDR (0.68) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753461 | 0.94 | KDR (0.68) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753456 | 0.94 | KDR (0.68) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753464 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753467 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL29153395 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL30753469 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL29153404 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 | |
| SCHEMBL29153412 | 0.92 | KDR (0.58) | KDRFLT1FLT4HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | claimed |
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | disclosed |