Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.67 |
| ▸ | FLT1 | P17948 | 1/20 | 0.67 |
| ▸ | FLT4 | P35916 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 16/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153394 | 1.00 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753473 | 1.00 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL29153408 | 1.00 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753465 | 1.00 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753457 | 1.00 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753470 | 0.93 | KDR (0.79) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753458 | 0.93 | KDR (0.79) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL30753475 | 0.93 | KDR (0.79) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL29153402 | 0.91 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 | |
| SCHEMBL29153399 | 0.91 | KDR (0.67) | KDRFLT1FLT4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | claimed |
| CN-117285518-A | Quinazoline derivative containing benzofuran structure and application thereof | 华侨大学 | 2023-12-26 | — | — | CN | disclosed |