Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 6/20 | 0.54 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158727 | 0.92 | TARBP2 (0.50) | KDM4EHPGDSMN1; SMN2TDP1NPSR1 | |
| SCHEMBL29158621 | 0.90 | KMT2A (0.54) | KDM4EHPGDTARBP2PDCD4MAPT | |
| SCHEMBL31466885 | 0.89 | TARBP2 (0.53) | KDM4EHPGDTARBP2PDCD4MAPT | |
| SCHEMBL29158788 | 0.89 | TARBP2 (0.66) | KDM4EHPGDNPSR1TARBP2PDCD4 | |
| SCHEMBL29158706 | 0.87 | TARBP2 (0.51) | KDM4EHPGDSMN1; SMN2TARBP2PDCD4 | |
| SCHEMBL29158606 | 0.87 | TARBP2 (0.63) | KDM4EHPGDTARBP2PDCD4MAPT | |
| SCHEMBL29158800 | 0.86 | TARBP2 (0.50) | KDM4EHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27189106 | 0.85 | SMN1; SMN2 (0.54) | KDM4EHPGDSMN1; SMN2TDP1NPSR1 | |
| SCHEMBL29158768 | 0.85 | TARBP2 (0.49) | KDM4EHPGDTARBP2PDCD4MAPT | |
| SCHEMBL29158607 | 0.85 | TARBP2 (0.55) | KDM4EHPGDSMN1; SMN2NPSR1TARBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |