Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069407 | 1.00 | USP30 (0.42) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL23069429 | 0.90 | USP30 (0.42) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL29158602 | 0.90 | USP30 (0.42) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL29158595 | 0.89 | USP30 (0.39) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL29158591 | 0.89 | USP30 (0.39) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL23085670 | 0.89 | USP30 (0.39) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL29770996 | 0.89 | USP30 (0.39) | USP30TNKSPARP2LRRK2CPT2 | |
| SCHEMBL23069424 | 0.89 | USP30 (0.44) | USP30TNKSPARP2LRRK2CHRM3 | |
| SCHEMBL29470214 | 0.89 | USP30 (0.44) | USP30TNKSPARP2LRRK2CHRM3 | |
| SCHEMBL23069418 | 0.88 | USP30 (0.42) | USP30TNKSPARP2LRRK2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341133-B | Substituted cyanopyrrolidines having USP30 inhibitor activity | 特殊治疗有限公司 | 2024-02-27 | — | — | CN | disclosed |