Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23085659 | 1.00 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL29158651 | 1.00 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL29770913 | 1.00 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL29158591 | 0.93 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL23085670 | 0.93 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL29158595 | 0.93 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL29770996 | 0.93 | USP30 (0.39) | USP30EGLN2NR1H2F2RCPT2 | |
| SCHEMBL23085655 | 0.89 | USP30 (0.39) | USP30NR1H2F2RKDM4D | |
| SCHEMBL29158578 | 0.89 | USP30 (0.39) | USP30NR1H2F2RKDM4D | |
| SCHEMBL29470220 | 0.89 | USP30 (0.39) | USP30NR1H2F2RKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341133-B | Substituted cyanopyrrolidines having USP30 inhibitor activity | 特殊治疗有限公司 | 2024-02-27 | — | — | CN | disclosed |