Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111214 | 0.88 | NR1H2 (0.57) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL29159652 | 0.88 | NR1H2 (0.44) | NR1H2RORCALOX5APFEN1MEN1 | |
| SCHEMBL71546 | 0.81 | NR1H2 (0.57) | NR1H2NAMPTUSP2SMN1; SMN2ALOX5AP | |
| SCHEMBL16607481 | 0.80 | NR1H2 (0.55) | NR1H2NAMPTUSP2SMN1; SMN2ALOX5AP | |
| SCHEMBL15019245 | 0.80 | NR1H2 (0.58) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL18015114 | 0.79 | NR1H2 (0.51) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL18991639 | 0.79 | NR1H2 (0.48) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL17220371 | 0.79 | NR1H2 (0.48) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL23585483 | 0.79 | NR1H2 (0.54) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL19768826 | 0.78 | NR1H2 (0.50) | NR1H2NAMPTRORCUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580824-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-02-20 | — | — | CN | disclosed |