Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17892101 | 0.91 | MAPT (0.63) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL28947059 | 0.89 | MAPT (0.61) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL7039215 | 0.86 | MAPT (0.57) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL23129547 | 0.86 | MAPT (0.57) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL1561571 | 0.84 | KCNN4 (0.58) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL27790710 | 0.84 | MAPT (0.55) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL2781433 | 0.81 | MAPT (0.68) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL368343 | 0.81 | MAPT (1.00) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL1560417 | 0.80 | MAPT (0.54) | MAPTKMT2AKCNN4CYP2C19HIF1A | |
| SCHEMBL14791242 | 0.80 | MAPT (0.50) | MAPTKMT2AKCNN4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117612715-A | NAFLD patient cardiovascular disease risk early screening model and establishment method | 华中科技大学同济医学院附属协和医院 | 2024-02-27 | — | — | CN | disclosed |
| CN-116332937-A | Dipeptidyl peptidase I inhibitors and uses thereof | 杭州邦顺制药有限公司 | 2023-06-27 | — | — | CN | disclosed |