Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 20/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.69 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.68 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.68 |
| ▸ | ERN2 | Q76MJ5 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714319 | 0.91 | PIK3CB (0.71) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL24713594 | 0.87 | PIK3CB (0.70) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL30768037 | 0.86 | PIK3CB (0.74) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL24715016 | 0.86 | PIK3CB (0.69) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL24713816 | 0.86 | PIK3CB (0.75) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL1639382 | 0.85 | PIK3CB (0.83) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL29826778 | 0.84 | PIK3CB (0.73) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL27221170 | 0.84 | PIK3CB (0.73) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL24713615 | 0.84 | PIK3CB (0.78) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL24715018 | 0.82 | PIK3CB (0.72) | PIK3CBPIK3CDPIK3CAPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615763-A | Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof | 健道生物医药有限公司 | 2024-02-27 | — | — | CN | disclosed |