Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 19/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.64 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825967 | 1.00 | PIK3CB (0.64) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL29160464 | 1.00 | PIK3CB (0.64) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL24713824 | 0.91 | PIK3CB (0.65) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL27231740 | 0.91 | PIK3CB (0.65) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL29826867 | 0.89 | PIK3CA (0.53) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL24713938 | 0.89 | PIK3CA (0.53) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL29826261 | 0.88 | PIK3CB (0.53) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL24714516 | 0.88 | PIK3CB (0.53) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL27231529 | 0.88 | PIK3CB (0.53) | PIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL24713841 | 0.87 | PIK3CA (0.50) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615763-A | Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof | 健道生物医药有限公司 | 2024-02-27 | — | — | CN | disclosed |