Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28949337 | 0.91 | TRPV1 (0.91) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5348698 | 0.90 | CYP1A2 (0.90) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14034814 | 0.89 | TRPV1 (0.93) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29160842 | 0.86 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL32666220 | 0.86 | CYP1A2 (0.78) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5889449 | 0.85 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5088067 | 0.85 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL679954 | 0.85 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Nonivamide SCHEMBL81939 | 0.85 | CYP1A2 (1.00) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6409250 | 0.85 | CYP1A2 (0.81) | TRPV1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412742-A | Capsaicin derivatives for the treatment of idiopathic pulmonary fibrosis | 艾辛全公司 | 2024-01-16 | — | — | CN | disclosed |