Benzene

Benzene

SCHEMBL29164330

FC(F)(F)c1cccnc1.c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.55
KIF11 P52732 1/20 0.55
TSHR P16473 2/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 3/20 0.51
CYP3A5 P20815 3/20 0.51
KCNA5 P22460 2/20 0.48
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387897 0.98 CYP19A1 (0.57) CYP19A1KIF11TSHRALDH1A1CYP3A4
SCHEMBL13577 0.98 CYP19A1 (0.57) CYP19A1KIF11TSHRALDH1A1CYP3A4
SCHEMBL7068828 0.98 CYP19A1 (0.57) CYP19A1KIF11TSHRALDH1A1CYP3A4
Ammonia Solution, Strong SCHEMBL28655959 0.95 CYP19A1 (0.55) CYP19A1KIF11TSHRALDH1A1CYP3A4
Water SCHEMBL27638122 0.95 CYP3A4 (0.56) CYP19A1KIF11TSHRALDH1A1CYP3A4
Bromide SCHEMBL29204966 0.95 CYP19A1 (0.55) CYP19A1KIF11TSHRALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL21796041 0.95 CYP19A1 (0.55) CYP19A1KIF11TSHRALDH1A1CYP3A4
Lithium SCHEMBL30216964 0.95 CYP19A1 (0.55) CYP19A1KIF11TSHRALDH1A1CYP3A4
Lithium Ion SCHEMBL28974295 0.93 CYP19A1 (0.53) CYP19A1KIF11TSHRALDH1A1CYP3A4
Hydrazine SCHEMBL28287990 0.93 CYP19A1 (0.53) CYP19A1KIF11TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304094-A Synthesis method of 3-trifluoromethyl pyridine or 3-difluoro methyl pyridine compound 瑞博(杭州)医药科技有限公司 2023-12-29 CN disclosed